– Benign
Dystrophic/Fat necrosis Ccoarse, irregular, lucent-centered, "lava-like" [from surgery, biopsy, minor trauma, radiation therapy]
Secretory Large, > 1 mm in diameter, rod-like, continuous +/- branching, bilateral, radiate from nipple in ductal distribution, age > 60 [plasma cell mastitis, duct ectasia]
Milk of calcium Morphology changes with position: pleomorphic/fuzzy on CC, teacup-like on ML/MLO [from
calcium layering in microcysts]
Popcorn Coarse, large, hyperdense [involuting fibroadenoma]
Skin Round/punctate, on skin en face, same configuration on different views = "tattoo sign"
Rim/Eggshell [Rim = oil cyst; Eggshell = calcified cyst wall]
Vascular Linear/parallel tracks coursing along blood vessels
Suture Linear/tubular +/- surgical knots
– Intermediate
Coarse Heterogeneous Irregular, conspicuous > 0.5mm, tend to coalesce but are smaller than dystrophic calcifications [DDx: fibroadenoma, fat necrosis, DCIS]
Amorphous Small, hazy, indistinct, "powdery" [40% benign, 20% high-risk, 20% DCIS]
– Suspicious
Fine Linear +/- Branching Thin, linear/curvilinear, irregular; dot-dash pattern; appearance suggests fillings of the lumen of a duct; "casting"
Fine Pleomorphic Varying sizes and shapes, more conspicuous than amorphous calcifications [25-40% risk of malignancy]
(Smithuis 2008)