IDC is the most common type of breast cancer (>70% of invasive breast cancers)

Treatment: Based on stage and receptor-status of tumor

Stage I  Surgery w/LN sampling, then RT (if BCS) and adjuvant systemic therapy based on tumor receptor-status

Stage II  Neoadjuvant systemic therapy may be given prior to surgery (to shrink tumor for BCS), surgery w/LN sampling, then RT (if BCS) and adjuvant systemic therapy based on tumor receptor-status

Stage III  Option 1) Neoadjuvant therapy first, followed by surgery w/ALND, followed by RT +/- adjuvant systemic therapy      Option 2) Surgery first (usually mastectomy) w/ALND, followed by RT and adjuvant systemic therapy

Stage IV  Palliative systemic therapy based on tumor receptor-status and patient symptoms. RT, surgery, regional chemotherapy for symptomatic relief (eg, mets pressing on spinal cord, to prevent bone fxs)

(Ikeda 2010, Georgian-Smith 2014, Bleiweiss 2013, Esserman 2014, ACS treatment 2016)

MALIGNANT BREAST DISORDERS:

Invasive Ductal Cancer (IDC)